Description
TRIPHAGE PG2 TABLET is an advanced fixed-dose combination therapy containing Pioglitazone and Glimepiride, designed to offer optimal glycemic control in patients with Type 2 Diabetes Mellitus. It is indicated for use when monotherapy is inadequate in maintaining blood glucose levels.
Glimepiride is a sulfonylurea that stimulates insulin release from pancreatic beta cells, helping reduce postprandial and fasting blood glucose.
Pioglitazone is a thiazolidinedione that improves insulin sensitivity in peripheral tissues and reduces hepatic glucose output.
Together, these agents provide a synergistic effect, enhancing insulin action and improving glucose uptake across multiple organs.
Oral Antidiabetic Combination
Glimepiride: Stimulates insulin secretion by acting on ATP-sensitive potassium channels in beta cells of the pancreas.
Pioglitazone: Activates PPAR-γ receptors, improving insulin sensitivity and glucose uptake in adipose tissue and muscle, while decreasing hepatic glucose production.
Type 2 Diabetes Mellitus (when monotherapy is inadequate)
Patients requiring dual oral antidiabetic therapy
Suitable for improving HbA1c levels in insulin-resistant patients
Dual-action approach for better glycemic control
Reduces both fasting and post-meal blood sugar levels
Enhances insulin sensitivity and pancreatic insulin release
Convenient once-daily dosing
Helps delay the need for insulin therapy in diabetic patients
Typically administered once daily, preferably with breakfast
Dosage to be individualized based on patient response and physician’s recommendation
Blood glucose monitoring is essential to determine efficacy and safety
Monitor liver function regularly due to Pioglitazone component
Use with caution in patients with heart failure
Risk of hypoglycemia, especially in elderly or those with renal impairment
Not recommended for Type 1 diabetes or diabetic ketoacidosis
Periodic monitoring of HbA1c and blood glucose is advised
Hypoglycemia
Weight gain
Edema
Headache
Muscle pain
Upper respiratory tract infections
At BLUEPILL EXPRESS, we pride ourselves on delivering pharmaceutical excellence through internationally certified facilities. TRIPHAGE PG2 TABLET is manufactured under WHO-GMP and ISO standards, ensuring safety, efficacy, and global compliance.
We are a global exporter of all types of medicines, supplying high-quality pharmaceutical products to markets across Asia, Africa, Latin America, CIS, and the Middle East. Our commitment to regulatory support, private labeling, and custom packaging makes us a preferred partner in third-party manufacturing.

