Description
PIPTASIGN Injection is a potent broad-spectrum β-lactam/β-lactamase inhibitor combination that consists of Piperacillin (a ureidopenicillin antibiotic) and Tazobactam (a β-lactamase inhibitor). This synergistic formulation enhances the activity of Piperacillin by preventing bacterial resistance mechanisms, particularly against organisms producing β-lactamase enzymes.
PIPTASIGN is widely used in the treatment of moderate to severe bacterial infections, including those of the respiratory tract, urinary tract, intra-abdominal area, skin and soft tissues, and gynecological infections. It is also commonly administered in cases of hospital-acquired infections, neutropenic fever, and sepsis.
This injection is manufactured under WHO-GMP, ISO, and stringent regulatory standards by BLUEPILL EXPRESS, a trusted global pharmaceutical manufacturer and exporter. The company offers PIPTASIGN Injection for third-party manufacturing, international distribution, and custom-label partnerships.
Broad-Spectrum Antibiotic
Anti-infective
β-lactam/β-lactamase Inhibitor Combination
Piperacillin: 4 g
Tazobactam: 0.5 g
Also available in 2.25 g and 1.125 g strengths (on request)
Effective against resistant gram-positive and gram-negative bacteria
Inhibits β-lactamase enzymes, enhancing antibiotic spectrum
Ideal for life-threatening infections in ICU and hospital settings
Reliable treatment for both aerobic and anaerobic pathogens
Injectable dosage ensures rapid systemic availability
Community-acquired and hospital-acquired pneumonia
Severe urinary tract infections (UTIs)
Intra-abdominal infections (including peritonitis)
Pelvic inflammatory disease
Complicated skin and soft tissue infections
Febrile neutropenia
Sepsis and bacteremia
Adults: Typically 4.5 g IV every 6–8 hours
Children: Dose based on body weight, under physician guidance
Administer via intravenous infusion over 20–30 minutes
Dosage adjustment may be required in renal impairment
Reconstitute with sterile water or appropriate IV diluent
Administer under medical supervision in sterile conditions
Complete full course even if symptoms improve early
Do not mix with other drugs in the same IV line unless confirmed compatible
Hypersensitivity to penicillins or cephalosporins
Caution in patients with renal dysfunction or electrolyte imbalance
Monitor liver enzymes and blood counts during prolonged therapy
Not recommended in viral infections (e.g., influenza)
Diarrhea
Injection site reactions
Nausea or vomiting
Elevated liver enzymes
Rare: Hypersensitivity reactions, thrombocytopenia
Form: Dry powder for IV injection
Strengths: 4.5 g / 2.25 g / 1.125 g
Pack Type: Glass vial with sterile water for injection (if required)
Shelf Life: 24 months
Storage: Store below 25°C; protect from light and moisture
Certifications: WHO-GMP, ISO 9001:2015, FDA (India)
BLUEPILL EXPRESS – A global leader in third-party pharmaceutical manufacturing and merchant export of high-quality medical formulations. Backed by state-of-the-art infrastructure and international certifications, BLUEPILL EXPRESS is committed to quality, safety, and efficacy in healthcare exports.
WHO-GMP certified global manufacturing facility
Customizable formulations and labeling for clients
Strict adherence to international pharmacopeial standards
Available for bulk export, contract manufacturing, and tender supply
Supported with complete COA, MSDS, and export documentation

