Description
AGOBLISS 25 TAB is a prescription medication that contains Agomelatine 25 mg, a modern antidepressant used in the treatment of major depressive disorder (MDD) and associated mood disturbances. Unique in its mechanism of action, Agomelatine works by acting as an agonist at melatonin receptors (MT1 and MT2) and an antagonist at serotonin 5-HT2C receptors. This dual activity helps reset the body’s circadian rhythm, improve sleep, and alleviate symptoms of depression without the typical side effects associated with conventional antidepressants.
AGOBLISS 25 TAB is suitable for adults suffering from depression-related insomnia, lack of motivation, sadness, anxiety, and fatigue. It is well-tolerated and has minimal sexual or weight-related side effects, making it a preferred choice for long-term depression management.
Agomelatine 25 mg – Melatonergic agonist and 5-HT2C antagonist
Major depressive disorder (MDD)
Depression with insomnia
Mood disorders and circadian rhythm disturbances
Stress-related mental fatigue
Resynchronizes sleep-wake cycles disturbed by depression
Enhances mood, motivation, and daily functioning
Non-sedating and free from withdrawal symptoms
Minimal impact on sexual function and weight
Suitable for long-term depression management
Well-tolerated in adult populations
Agomelatine mimics melatonin to reset the body clock (circadian rhythm) and blocks 5-HT2C receptors, which enhances dopamine and norepinephrine release in the frontal cortex. This dual action improves both sleep quality and mood regulation—two key factors in managing depression effectively.
Typically one tablet (25 mg) taken orally at bedtime
Can be increased to 50 mg/day under medical supervision
Should be taken at the same time every night
Do not exceed the recommended dose
Not suitable for patients with liver impairment
Regular liver function monitoring required during treatment
Avoid alcohol and other CNS depressants
Not recommended during pregnancy or breastfeeding unless advised
Report any signs of jaundice, fatigue, or nausea to your doctor
Headache, dizziness, nausea, or mild gastrointestinal disturbances
Transient anxiety or vivid dreams
Elevated liver enzymes (rare) – requires monitoring
Generally fewer side effects than SSRIs or SNRIs
AGOBLISS 25 TAB is proudly manufactured and distributed by Bluepill Express, a globally recognized pharmaceutical exporter. Specializing in third-party manufacturing and private labeling, Bluepill Express supplies WHO-GMP certified pharmaceutical products to over 140 countries.
Europe (Western & Eastern)
Africa (North, Sub-Saharan)
Middle East and GCC
Southeast Asia and South Asia
CIS Nations and Latin America
Australia and Pacific Islands
WHO-GMP and ISO-certified manufacturing
Strict international quality compliance
Private label and custom branding options available
Full regulatory support: COA, MSDS, FSC, and other docs
Fast and reliable export logistics
AGOBLISS 25 TAB represents Bluepill Express’s commitment to mental health and patient well-being. With a strong distribution and support network, Bluepill Express delivers high-quality psychiatric medications to global healthcare providers and distributors.

