Description
SIGNATRET 20 Softgel Capsule is a high-potency oral retinoid formulation containing Isotretinoin 20 mg, a derivative of vitamin A, primarily used in the treatment of severe recalcitrant acne, particularly nodular or cystic acne that is unresponsive to conventional topical or systemic therapies. Isotretinoin acts by reducing the size and activity of the sebaceous glands, thereby decreasing sebum production and inhibiting acne-causing bacteria and inflammation.
This medication also helps normalize the process of skin cell shedding, preventing clogged pores. SIGNATRET 20 is a systemic therapy typically prescribed under strict medical supervision due to its effectiveness and potential side effects.
Manufactured under world-class quality control systems by BLUEPILL EXPRESS, this product meets the global demand for advanced acne treatments with assured compliance, safety, and efficacy. BLUEPILL EXPRESS offers third-party manufacturing and export services for SIGNATRET 20 Softgel Capsule, meeting the needs of dermatologists, hospitals, pharmacies, and wholesalers worldwide.
Severe nodular acne
Cystic acne unresponsive to antibiotics or topical treatments
Acne conglobata
Other skin conditions as determined by a dermatologist (e.g., severe rosacea or folliculitis)
Reduces sebum production and inflammation
Clears deep, cystic, and scarring acne over time
Offers long-term remission from severe acne
Administered as a once or twice daily softgel capsule
Improves overall skin texture and clarity with proper medical monitoring
Strict pregnancy prevention is essential during and after treatment due to high teratogenic risk
Requires periodic liver function tests, lipid monitoring, and pregnancy tests
Should only be used under close medical supervision
Not suitable for use in breastfeeding women or patients with severe liver dysfunction
May cause dryness of lips, skin, and eyes, which are manageable with supportive care
BLUEPILL EXPRESS is a globally recognized third-party manufacturing and export company known for its adherence to:
WHO-GMP, ISO, and regulatory certifications
Advanced softgel encapsulation technology
Controlled environment facilities for moisture-sensitive formulations
Global standard packaging (blister, strip, and bottle options)
End-to-end support with regulatory documentation including FSC, COA, MSDS, CTD, and more
As a global pharmaceutical exporter, BLUEPILL EXPRESS supplies SIGNATRET 20 Softgel Capsule to:
Dermatology clinics and hospitals
Exporters and wholesalers across Africa, Southeast Asia, Middle East, CIS, and Latin America
Tender-based government and private sector procurement systems
Online platforms and medical distribution companies
With unmatched flexibility in branding, custom labeling, and MOQ-based pricing, BLUEPILL EXPRESS is a preferred partner for skin care and acne product solutions across global markets.
Swallow the softgel whole with water, usually once or twice daily with food
Follow dosage exactly as prescribed by the healthcare professional
Avoid vitamin A supplements during therapy
Avoid cosmetic skin treatments such as waxing or laser procedures during and for 6 months after therapy

