Description
METATILE 3 TABLET is a fixed-dose combination tablet designed to manage Type 2 Diabetes Mellitus in adult patients. It integrates three well-established anti-diabetic agents—Glimepiride, Pioglitazone, and Metformin—that work synergistically to regulate blood glucose levels by addressing insulin resistance, stimulating insulin secretion, and decreasing hepatic glucose production.
Glimepiride: A sulfonylurea that stimulates pancreatic beta cells to produce insulin. It is fast-acting and long-lasting, helping to lower blood sugar effectively, especially after meals.
Pioglitazone: A thiazolidinedione that enhances insulin sensitivity in muscle and adipose tissue. It improves glucose uptake without increasing insulin levels.
Metformin: A biguanide that reduces hepatic glucose output and increases peripheral glucose uptake, thereby lowering both fasting and postprandial blood glucose levels.
The combination of these three agents in a single tablet offers comprehensive blood sugar control and is especially beneficial for patients requiring escalation from dual to triple therapy.
Management of Type 2 Diabetes Mellitus in adults
For patients inadequately controlled on dual therapy (Metformin + Glimepiride or Pioglitazone)
To improve insulin sensitivity, reduce insulin resistance, and optimize pancreatic insulin secretion
Multi-mechanism approach for superior glycemic control
Reduces fasting and postprandial blood glucose levels
Minimizes risk of diabetes-related complications
Convenient once-daily dosage
Manufactured by Bluepill Express, ensuring international quality and regulatory compliance
Typically taken once daily with meals, as directed by a physician
Dosage may vary based on blood glucose levels and clinical condition
Regular monitoring of blood sugar, liver function, and kidney function is recommended
Not recommended for Type 1 diabetes or diabetic ketoacidosis
Use with caution in patients with renal or hepatic impairment
Risk of hypoglycemia when used with other anti-diabetic agents or missed meals
May cause weight gain due to pioglitazone
Contraindicated in heart failure, bladder cancer, and severe kidney dysfunction
Hypoglycemia
Nausea, diarrhea
Weight gain
Headache
Edema
Muscle pain or fatigue
Patients should promptly report any signs of lactic acidosis, urinary discomfort, or jaundice.
Bluepill Express is a globally recognized third-party pharmaceutical manufacturer with certifications including WHO-GMP, ISO, and other international accreditations. With a robust export network across 140+ countries, Bluepill Express ensures the delivery of high-quality, cost-effective medications with complete documentation support, including COA, MSDS, and stability data.
The company specializes in custom formulations, bulk orders, and regulatory-compliant packaging, making it a trusted partner for pharmacies, hospitals, and distributors worldwide.
